Species: Hu
Applications: WB, ELISA, Func, ICC/IF, IHC, IP
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, KD
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, IHC, IP, ChIP
Host: Rabbit Polyclonal
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
TIF1 alpha is encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Bioinformatics
Entrez |
Mouse Human |
Uniprot |
Human Human Human Human |
Product By Gene ID |
8805 |
Alternate Names |
- E3 ubiquitin-protein ligase TRIM24
- EC 6.3.2
- EC 6.3.2.-
- hTIF1
- PTC6
- RING finger protein 82
- RNF82Tif1a
- TIF1-alpha
- TIF1ATIF1ALPHA
- TIF1TF1A
- transcription intermediary factor 1-alpha
- transcriptional intermediary factor 1
- tripartite motif containing 24
- tripartite motif-containing 24
- Tripartite motif-containing protein 24
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Research Areas for TIF1 alpha
Find related products by research area and learn more about each of the different research areas below.
Protein KinaseZinc Finger