Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Ca
Applications: WB, ELISA, ICC/IF, IHC
Host: Goat Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, Func, MA, PAGE, AP
Species: Hu
Applications: AC
Description
The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
7072 |
| Alternate Names |
- cytotoxic granule-associated RNA-binding protein
- nucleolysin TIA-1 isoform p40
- p40-TIA-1 (containing p15-TIA-1)
- p40-TIA-1
- RNA-binding protein TIA-1
- T-cell-restricted intracellular antigen-1
- TIA1 cytotoxic granule-associated RNA binding protein
- TIA1 cytotoxic granule-associated RNA-binding protein
- TIA-1
|
