TBP like protein TLP Products

Description

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes.

Bioinformatics

Entrez	237336 Mouse 9519 Human
Uniprot	AAH17559 Human NM_004865 Human NP_004856 Human NP_004856. Human
Product By Gene ID	9519
Alternate Names	21 kDa TBP-like protein STUD21-kDA TBP-like protein TATA box binding protein-related factor 2 TATA box-binding protein-like protein 1 TATA box-binding protein-related factor 2 TBP-like 1 TBP-like factor TBP-like protein 1 TBP-related factor 2 TBP-related protein TLFMGC:8389 TLP21 TLPMGC:9620 TRF2Second TBP of unique DNA protein TRP