TAP1 Products

Description

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease.

Bioinformatics

Entrez	6890 Human
Uniprot	A41538 Human AAH14081 Human NP_000584.2 Human Q03518 Human
Product By Gene ID	6890
Alternate Names	ABC transporter, MHC 1 ABCB2FLJ41500 antigen peptide transporter 1 APT1 ATP-binding cassette sub-family B member 2 ATP-binding cassette, sub-family B (MDR/TAP), member 2 D6S114E Peptide supply factor 1 Peptide transporter involved in antigen processing 1 Peptide transporter PSF1 Peptide transporter TAP1 PSF-1 PSF1ABC17 Really interesting new gene 4 protein RING4FLJ26666 TAP1*0102N TAP1N transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) transporter associated with antigen processing transporter, ATP-binding cassette, major histocompatibility complex, 1 Y3

Research Areas for TAP1

Find related products by research area and learn more about each of the different research areas below.

Cell Biology
Diabetes Research
Membrane Trafficking and Chaperones