STK4 Products

Description

STK4 is encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.

Bioinformatics

Entrez	311622 Rat 58231 Mouse 6789 Human
Uniprot	AAA83254.1 Human AAH05231 Human NM_006282 Human NM_006282.2 Human NP_006273 Human Q13043 Human
Product By Gene ID	6789
Alternate Names	EC 2.7.11 EC 2.7.11.1 kinase responsive to stress 2 KRS2KRS2)) Mammalian STE20-like protein kinase 1 mammalian sterile 20-like 1 MST-1 MST1DKFZp686A2068 serine/threonine kinase 4 serine/threonine-protein kinase 4 Serine/threonine-protein kinase Krs-2 STE20-like kinase MST1

Research Areas for STK4

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Phospho-Specific