SNW1 Products

Description

SNW1, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.

Bioinformatics

Entrez	22938 Human 66354 Mouse
Uniprot	NP_036377 Human Q13573 Human
Product By Gene ID	22938
Alternate Names	Bx42 homolog of Drosophila BX42 MGC119379 NCoA-62 NCOA-62 Nuclear protein SkiP Nuclear receptor coactivator NCoA-62 nuclear receptor coactivator, 62-kD Prp45 PRPF45 SKI interacting protein Ski-interacting protein SKIPSKIIP SNW domain containing 1 SNW domain-containing protein 1