Semaphorin 4G Products

Description

Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. This gene encodes a class 4 semaphorin. This gene and the gene for mitochondrial ribosomal protein L43 overlap at map location 10q24.31 and are transcribed in opposite directions.

Bioinformatics

Entrez	57715 Human
Uniprot	AAH20960 Human AAH20960.1 Human NP_060363 Human Q9NTN9 Human
Product By Gene ID	57715
Alternate Names	KIAA1619FLJ20590 MGC102867 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and shortcytoplasmic domain, (semaphorin) 4G semaphorin-4G

Research Areas for Semaphorin 4G

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Neuroscience