Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Bv
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
SCYL1 encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human |
Product By Gene ID |
57410 |
Alternate Names |
- Coated vesicle-associated kinase of 90 kDa
- CVAK90
- GKLPTelomerase transcriptional element-interacting factor
- likely ortholog of mouse N-terminal kinase-like protein
- MGC78454
- NKTL
- N-terminal kinase-like protein
- NTKLN-terminal kinase-like
- P105
- SCY1-like 1 (S. cerevisiae)
- TAPKTeratoma-associated tyrosine kinase
- TEIFSCY1-like protein 1
- Telomerase regulation-associated protein
- telomerase transcriptional elements-interacting factor
- TRAPHT019
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Research Areas for SCYL1
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Protein Kinase