RRAGB Products

Description

Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq]

Bioinformatics

Entrez	10325 Human
Uniprot	AAH34726 Human NM_006064 Human NP_057740.2 Human Q5VZM2 Human
Product By Gene ID	10325
Alternate Names	bA465E19.1 GTP-binding protein ragB Rag B RagB RAGB Ras-related GTP binding B ras-related GTP-binding protein B

Research Areas for RRAGB

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Cancer
mTOR Pathway