Species: Hu, Mu, Rt, Po, Bv, Ca, Ch, Sh, Xp
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Rabbit Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Description
Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.
Bioinformatics
| Entrez |
Mouse
Human
Rat
|
| Uniprot |
Human
Human
Human
Human
Human
|
| Product By Gene ID |
388 |
| Alternate Names |
- ARH6MSTP081
- ARHBAplysia RAS-related homolog 6
- h6
- MST081
- oncogene RHO H6
- ras homolog gene family, member B
- Rho cDNA clone 6
- RHOH6RhoB
- rho-related GTP-binding protein RhoB
|
Research Areas for RhoB
Find related products by research area and learn more about each of the different research areas below.
Angiogenesis
