RFX2 Products

Description

RFX2 is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq]

Bioinformatics

Entrez	5990 Human
Uniprot	AAH28579.1 Human NM_000635 Human NP_000626 Human P48378 Human
Product By Gene ID	5990
Alternate Names	DNA binding protein RFX2 DNA-binding protein RFX2 FLJ14226 HLA class II regulatory factor RFX2 Regulatory factor X 2 regulatory factor X, 2 (influences HLA class II expression) trans-acting regulatory factor 2