Species: Hu, Mu, Rt
Applications: WB, Func, ICC/IF, IHC, IP
Host: Mouse Monoclonal
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IP
Host: Mouse Monoclonal
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Description
The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human Human Human |
Product By Gene ID |
5906 |
Alternate Names |
- C21KG
- G-22K
- GTP-binding protein smg p21A
- KREV-1
- KREV1Ras-related protein Krev-1
- RAP1
- RAP1A, member of RAS oncogene family
- RAS-related protein RAP1A
- ras-related protein Rap-1A
- SMGP21
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