RAE1 Products

Description

Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Bioinformatics

Entrez	362281 Rat 66679 Mouse 8480 Human
Uniprot	NM_003610 Human NP_001015885 Human NP_003601.1 Human P78406 Human
Product By Gene ID	8480
Alternate Names	dJ481F12.3 dJ800J21.1 FLJ30608 homolog of yeast Rae1 (Bharathi) mRNA-associated protein of 41 kDa (Kraemer) MGC117333 MGC126076 MGC126077 MIG14 migration-inducing gene 14 Mnrp41 mRNA export factor mRNA export protein mRNA-associated protein mrnp 41 mRNA-binding protein, 41-kD MRNP41 RAE1 (RNA export 1, S.pombe) homolog Rae1 protein homolog RAE1 RNA export 1 homolog (S. pombe)