PTP alpha/PTPRA Products

Description

PTP alpha is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.

Bioinformatics

Entrez	5786 Human
Uniprot	NM_002836 Human NM_080841 Human NP_002827 Human NP_543030 Human P18433 Human
Product By Gene ID	5786
Alternate Names	EC 3.1.3.48 HEPTP LRPHPTPalpha protein tyrosine phosphatase, receptor type, A Protein-tyrosine phosphatase alpha PTPAreceptor type, alpha polypeptide PTPLCA-related phosphatase receptor-type tyrosine-protein phosphatase alpha RPTPA R-PTP-alpha tyrosine phosphatase alpha

Research Areas for PTP alpha/PTPRA

Find related products by research area and learn more about each of the different research areas below.

GPCR
Phospho-Specific
Protein Phosphatase
Signal Transduction