PTF1A Products

Description

PTF1A encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers.

Bioinformatics

Entrez	117034 Rat 19213 Mouse 256297 Human
Uniprot	NP_835455 Human NP_835455.1 Human Q7RTS3 Human
Product By Gene ID	256297
Alternate Names	bHLH transcription factor p48 BHLHA29 bHLHa29exocrine pancreas-specific transcription factor p48 Class A basic helix-loop-helix protein 29 p48 DNA-binding subunit of transcription factor PTF1 pancreas specific transcription factor, 1a pancreas transcription factor 1 subunit alpha Pancreas-specific transcription factor 1a PTF1P48 PTF1-p48class II bHLH protein PTF1A

Research Areas for PTF1A

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Protein Kinase