Protein Disulfide Isomerase/P4HB Products

Description

P4HB, the beta subunit of prolyl 4-hydroxylase, a highly abundant member of the PDI family. P4HB is a multifunctional enzyme, involved in hydroxylation of prolyl residues in preprocollagen, as well as continual rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.

Bioinformatics

Uniprot	NP_000909 Human NP_000909.2 Human P07237 Human
Product By Gene ID	5034
Alternate Names	Cellular thyroid hormone-binding protein collagen prolyl 4-hydroxylase beta DSI ERBA2L GIT glutathione-insulin transhydrogenase P4Hbeta p55 PDIA1procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), betapolypeptide (protein disulfide isomerase-associated 1) PDIEC 5.3.4.1 PHDB PO4DB PO4HB procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), betapolypeptide PROHBprocollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), betapolypeptide (protein disulfide isomerase; thyroid hormone binding protein p55) Prolyl 4-hydroxylase subunit beta prolyl 4-hydroxylase, beta polypeptide protein disulfide isomerase family A, member 1 protein disulfide isomerase/oxidoreductase protein disulfide isomerase-associated 1 protein disulfide-isomerase protocollagen hydroxylase thyroid hormone-binding protein p55

Research Areas for Protein Disulfide Isomerase/P4HB

Find related products by research area and learn more about each of the different research areas below.

Cellular Markers
ER Markers
Fibroblast Cell Markers
Hypoxia