PDIA2 Products

Description

This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, two TRX-like domains and a C-terminal ER-retention sequence. The protein plays a role in the folding of nascent proteins in the endoplasmic reticulum by forming disulfide bonds through its thiol isomerase, oxidase, and reductase activity. The encoded protein also possesses estradiol-binding activity and can modulate intracellular estradiol levels.

Bioinformatics

Uniprot	NP_006840 Human NP_006840.2 Human P04785 Rat Q13087 Human
Product By Gene ID	64714
Alternate Names	Pancreas-specific protein disulfide isomerase pancreatic protein disulfide isomerase PDA2 PDI PDIp PDIR protein disulfide isomerase, pancreatic protein disulfide isomerase-associated 2 protein disulfide-isomerase A2 Rho GDP dissociation inhibitor gamma

Research Areas for PDIA2

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cellular Markers
ER Markers
Fibroblast Cell Markers
Hypoxia