Species: Hu, Mu, Rt
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Ch
Applications: WB, ELISA, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Po, Bv, Sh
Applications: WB, DB, ELISA, IHC, IP, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
PDE5A encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
Bioinformatics
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
8654 |
| Alternate Names |
- CGB-PDE
- cGMP-binding cGMP-specific 3'-5'-cyclic nucleotide phosphodiesterase
- cGMP-binding cGMP-specific phosphodiesterase
- cGMP-specific 3'-5'-cyclic phosphodiesterase
- cGMP-specific phosphodiesterase type 5A
- CN5A
- EC 3.1.4
- EC 3.1.4.35
- PDE5
- phosphodiesterase 5A, cGMP-specific
- phosphodiesterase isozyme 5
|
