PBEF/Visfatin/NAMPT Products

Description

NAMPT encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity. This gene has a pseudogene on chromosome 10.

Bioinformatics

Uniprot	NM_182790 Human NP_005737.1 Human P43490 Human
Product By Gene ID	10135
Alternate Names	EC 2.4.2.12 MGC117256 NAmPRTase Nampt nicotinamide phosphoribosyltransferase PBEF1110035O14Rik PBEF1DKFZp666B131 Pre-B cell-enhancing factor pre-B-cell colony enhancing factor 1 Pre-B-cell colony-enhancing factor 1 VF Visfatin VISFATIN

Research Areas for PBEF/Visfatin/NAMPT

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Cell Cycle and Replication
Immunology
Innate Immunity