PARD6A Products

Description

his gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Bioinformatics

Uniprot	NM_001037281 Human NP_001032358 Human NP_001032358.1 Human NP_058644 Human NP_058644. Human
Product By Gene ID	50855
Alternate Names	PAR-6 alpha par-6 partitioning defective 6 homolog alpha (C. elegans) PAR-6 PAR6A PAR6alpha PAR-6Apar-6 (partitioning defective 6, C.elegans) homolog alpha PAR6C partitioning defective 6 homolog alpha partitioning defective-6 homolog alpha partitioning-defective protein 6 Tax interaction protein 40 TAX40 Tax-interacting protein 40 TIP-40PAR6

Research Areas for PARD6A

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Cell Cycle and Replication