P2X2/P2RX2 Products

Description

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. P2X2 has two putative transmembrane domains with intracellular N and C-termini. It can form homomeric channels and heteromeric channels with other members of the family. Six transcript variants encoding six distinct isoforms have been identified for this gene. P2X2 is expressed in brain, spinal cord, sensory and autonomic ganglia as well as in neuroendocrine cells.

Bioinformatics

Uniprot	NP_036358.2 Human NP_733783 Human NP_777362.1 Human Q8K3P1 Mouse Q9UBL9 Human
Product By Gene ID	22953
Alternate Names	ATP receptor MGC129601 P2X purinoceptor 2 P2X2P2X Receptor, subunit 2 purinergic receptor P2X, ligand-gated ion channel, 2 Purinergic receptor

Research Areas for P2X2/P2RX2

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Signal Transduction