NUP133 Products

Description

The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. The nucleoporin protein encoded by this gene displays evolutionarily conserved interactions with other nucleoporins. This protein, which localizes to both sides of the nuclear pore complex at interphase, remains associated with the complex during mitosis and is targeted at early stages to the reforming nuclear envelope. This protein also localizes to kinetochores of mitotic cells.

Bioinformatics

Uniprot	NM_018230 Human NP_060700 Human
Product By Gene ID	55746
Alternate Names	FLJ10814 hNUP133,133 kDa nucleoporin MGC21133 nuclear pore complex protein Nup133 nucleoporin 133kD nucleoporin 133kDa Nucleoporin Nup133