NME6 Products

Description

Belonging to the NDK family, NME6 plays an important role in cell growth and is commonly expressed in the kidney, prostate, ovary and intestine. This gene is an inhibitor of p53 induced apoptosis and is a ubiquitous enzyme that catalyzes the transfer of gamma-phosphates. NME6 also phosphorylates nucleoside diphosphates; and is involved in the regulation of development, oncogenic transformation and metastasis. It also plays a major role in the synthesis of nucleoside triphosphates other than ATP. Molecular functions include ATP binding, kinase activity, metal ion binding, nucleoside diphosphate kinase activity, nucleotide binding and transferase activity. Diseases for NME6 include neisseria meningitides, prostatitis, prostate cancer and pneumonia.

Bioinformatics

Uniprot	AAH01808 Human AAH01808.1 Human AAH12828 Human NM_005793 Human NP_005784 Human NP_005784.1 Human O75414 Human
Product By Gene ID	10201
Alternate Names	EC 2.7.4.6 Inhibitor of p53-induced apoptosis-alpha IPIA-alpha IPIA-ALPHA NDK 6 NDP kinase 6 nm23-H6 NM23-H6 non-metastatic cells 6, protein expressed in (nucleoside-diphosphate kinase) nucleoside diphosphate kinase 6

Research Areas for NME6

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Lipid and Metabolism