NAT1 Products

Description

NAT1 is a gene that codes for a protein that helps in the detoxification of various hydrazine and arylamine drugs as well as to bioactivate several carcinogens and is 290 amino acids long with a weight of approximately 34 kDa. Current studies are being done on several diseases and disorders related to this gene including neural tube defect, drug-induced hepatitis, talipes equinovarus, spina bifida, multiple chemical sensitivity, malignant pleural mesothelioma, non-Hodgkin lymphoma, cleft palate, familial adenomatous polyposis, substance abuse, orofacial cleft, peptic ulcer, lymphoblastic leukemia, systemic lupus erythematosus, cystic fibrosis, lupus erythematosus, Hodgkin's lymphoma, inflammatory bowel disease, and motor neuron disease. NAT1 has also been shown to have interactions with NAA10, SNTA1, SYP1A2, CYP2A6, and XDH in pathways such as the arylamine metabolism, acetylation, and drug metabolism pathways.

Bioinformatics

Uniprot	NP_000653 Human NP_000653.3 Human NP_001153644 Human P18440 Human
Product By Gene ID	9
Alternate Names	AAC1N-acetyltransferase type 1 Arylamide acetylase 1 arylamine N-acetyltransferase 1 EC 2.3.1.5 MNAT Monomorphic arylamine N-acetyltransferase N-acetyltransferase 1 (arylamine N-acetyltransferase) NAT-1 NATI