MYL9 Products

Description

Myosin is the major component of thick muscle filaments, and is a long asymmetric molecule containing a globular head and a long tail. The molecule consists of two heavy chains each ~200,000 daltons, and four light chains each ~16,000 - 21,000 daltons. Activation of smooth and cardiac muscle primarily involves pathways that increase calcium and myosin phosphorylation resulting in contraction. Myosin light chain phosphatase acts to regulate muscle contraction by dephosphorylating activated myosin light chain. The selected peptide sequence used to generate the polyclonal antibody is located near the amino terminal end of the polypeptide corresponding to the smooth/non-muscle form of myosin regulatory light chain found in cardiac myocytes in addition to smooth and non-muscle cells. This sequence differs from that of the sarcomeric/ cardiac form of myosin regulatory light chain that has a different sequence around the phosphorylation site. Human, mouse and rat have almost identical sequences.

Bioinformatics

Uniprot	AAH02648 Human AAH02648.1 Human NM_181526 Human NP_006088 Human P24844 Human
Product By Gene ID	10398
Alternate Names	LC2020 kDa myosin light chain MLC2Myosin RLC MRLC1MLC-2C myosin regulatory light chain 1 Myosin regulatory light chain 2, smooth muscle isoform Myosin regulatory light chain 9 Myosin regulatory light chain MRLC1 myosin regulatory light polypeptide 9 myosin, light chain 9, regulatory myosin, light polypeptide 9, regulatory MYRL2MGC3505

Research Areas for MYL9

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Phospho-Specific