Muscleblind-like 1 Products

Description

Several important human diseases are associated with expansion of polynucleotide sequences, in most cases trinucleotide repeats. Myotonic dystrophy (DM1) is one of these diseases, and is associated with increases in the number of CTG repeats in the UTR of the gene encoding myotonin (a.k.a. DM Kinase, DMK or myotonin-Protein Kinase), a ser/thr kinase expressed specifically in muscle. Mammalian genomes contain three muscleblind-like proteins, generally referred to as MBNL1, MBNL2 and MBNL3, and all three were found to associate with long double stranded CUG RNA repeats, thus, being triplet repeat expansion dsRNA-binding proteins.

Bioinformatics

Entrez	4154 Human
Uniprot	AAH43493 Human AAH50535 Human NM_207296 Human NP_066368 Human NP_066368.2 Human NP_997179 Human Q9NR56 Human
Product By Gene ID	4154
Alternate Names	DKFZp686P06174 EXP40 EXP42 EXPKIAA0428EXP35 MBNL muscleblind (Drosophila)-like muscleblind-like (Drosophila) muscleblind-like protein 1 Triplet-expansion RNA-binding protein

Research Areas for Muscleblind-like 1

Find related products by research area and learn more about each of the different research areas below.

Chromatin Research
DNA replication, Transcription, Translation and Splicing