MSH4 Products

Description

The Escherichia coli MutHLS system has been highly conserved throughout evolution. The eukaryotic pathway results in a specialization of MutS homologs such as MSH2 that have evolved to play crucial roles in both DNA mismatch repair and meiotic recombination. In Saccharomyces cerevisiae, MSH4 is a meiosis-specific protein that is not involved in mismatch correction. This protein is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I.

Bioinformatics

Entrez	4438 Human
Uniprot	NP_002431 Human NP_002431.2 Human O15457 Human
Product By Gene ID	4438
Alternate Names	hMSH4 mutS (E. coli) homolog 4 mutS homolog 4 (E. coli) mutS protein homolog 4

Research Areas for MSH4

Find related products by research area and learn more about each of the different research areas below.

DNA Repair
Mismatch Repair