Species: Rt
Applications: WB, IHC, B/N
Host: Goat Polyclonal
Species: Hu
Applications: WB, ELISA, IHC, B/N
Host: Sheep Polyclonal
Species: Hu
Applications: ELISA
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: Binding Activity
Species: Rt
Applications: Binding Activity
Description
AMHR2 is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins that is expressed in fetal and adult gonads of both sexes. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth; anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. A number of allelic variants of AMHR2 are associated with persistent mullerian duct syndrome.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human |
Product By Gene ID |
269 |
Alternate Names |
- AMH type II receptor
- AMHREC 2.7.11.30
- MISR2
- MISRIIMIS type II receptor
- MRII
- Muellerian hormone type II receptor
- Muellerian hormone type-2 receptor
- Mullerian hormone receptor, type II
- Mullerian inhibiting substance type II receptor
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Research Areas for MIS RII/AMHR2
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Protein Kinase