Species: Hu, Rt
Applications: WB, IP (-)
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Description
Defects in the Midline-1 (MID1) gene are the cause of Opitz syndrome, an X-linked recessive disorder characterized by developmental defects. MID1 is a microtubule-associated protein (MAP) with E3 ubiquitin ligase activity. MID1 has been shown to target protein phosphatases 2A (PP2Ac) on microtubules for degradation. MID1 association with PP2A has been proposed to regulate microtubule stabilization for cellular processes such as cell division and migration.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human Human Human |
Product By Gene ID |
4281 |
Alternate Names |
- EC 6.3.2.-
- FLJ57031
- FLJ58683
- FLJ76288
- FXYGBBB1
- Midin
- midline 1 (Opitz/BBB syndrome)
- RNF59MIDIN
- TRIM18mouse, homolog of
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Research Areas for MID1
Find related products by research area and learn more about each of the different research areas below.
Lipid and MetabolismZinc Finger
Related MID1 Blog Posts
Check out the latest blog posts on MID1.
Beta Tubulin III and neurogenesis
Beta tubulin III, also known as Tuj-1, is a class III member of the beta tubulin protein family. Beta tubulins are one of two structural components that form our microtubule network. While general tubulins play a role in a wide range of cellular pr... Read more.
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Read more MID1 related blogs.