Meprin beta Subunit/MEP1B Products

Description

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes and in leukocytes and certain cancer cells. Mature meprins are oligomers of evolutionarily related, separately encoded alpha and/or beta subunits. Homooligomers of meprin-alpha are secreted; oligomers containing meprin-beta are associated with the plasma membrane. Substrates include bioactive peptides and extracellular matrix proteins.

Bioinformatics

Entrez	4225 Human
Uniprot	Q16820 Human
Product By Gene ID	4225
Alternate Names	EC 3.4.24.63 Endopeptidase-2 endopeptidase-2 meprin A subunit beta meprin A, beta Meprin B N-benzoyl-L-tyrosyl-p-amino-benzoic acid hydrolase beta subunit N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta PABA peptide hydrolase PPH beta