Species: Hu, Mu, Bv
Applications: WB, ELISA, ICC/IF, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Ca
Applications: WB, ELISA
Host: Goat Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
MCG10 encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined.
Bioinformatics
Entrez |
Rat Human Mouse |
Uniprot |
Human Human Human |
Product By Gene ID |
57060 |
Alternate Names |
- alphaCP-4 protein
- alpha-CP4
- Alpha-CP4
- CBP
- LIP4
- LYST-interacting protein
- MCG10
- poly(rC) binding protein 4
- poly(rC)-binding protein 4
- RNA binding protein MCG10
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