Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu, Mu
Applications: WB, ELISA, Flow
Host: Goat Polyclonal
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
MARK4 contains an N terminal serine/threonine kinase domain, a central ubiquitin associated domain, and a C terminal KA1 associated kinase domain. RT PCR analysis detects upregulated expression of the gene for MARK4 in nearly all clinical hepatocellular carcinoma cells. Northern blot analysis reveals ubiquitous expression of a 3.6kb transcript, with highest expression in testis. Immunofluorescence microscopy demonstrates homogeneous cytoplasmic expression. Colony forming assays show that MARK4 antisense reduces the growth of SNU475 cells. It has been suggested that MARK4 provides a growth advantage to cells.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human Human |
Product By Gene ID |
57787 |
Alternate Names |
- EC 2.7.11
- EC 2.7.11.1
- FLJ12177
- FLJ90097
- KIAA1860MARK4L
- MAP/microtubule affinity-regulating kinase 4
- MAP/microtubule affinity-regulating kinase like 1
- MAP/microtubule affinity-regulating kinase-like 1
- MARK4 serine/threonine protein kinase
- MARKL1L
- MARKL1MARK4S
- Nbla00650
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Research Areas for MARK4
Find related products by research area and learn more about each of the different research areas below.
Apoptosis