MAPRE1 Products

Description

End -binding protein 1 (EB1) is a member of the RP/EB family and was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. EB1 also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that EB1 is involved in the regulation of microtubule structures and chromosome stability. [rom NCBI GeneID:22919]

Bioinformatics

Entrez	22919 Human
Uniprot	NM_012325 Human NP_036457 Human NP_036457.1 Human Q15691 Human
Product By Gene ID	22919
Alternate Names	adenomatous polyposis coli-binding protein EB1 APC-binding protein EB1 EB1MGC129946 End-binding protein 1 MGC117374 microtubule-associated protein RP/EB family member 1 microtubule-associated protein, RP/EB family, member 1

Research Areas for MAPRE1

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Mitotic Regulators