Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Description
LOXL3 encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Alternatively spliced transcript variants of this gene have been reported but their full-length nature has not been determined.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
|
| Product By Gene ID |
84695 |
| Alternate Names |
- EC 1.4.3
- EC 1.4.3.-
- EC 1.4.3.13
- LOXL
- lysyl oxidase homolog 3
- lysyl oxidase-like 3
- Lysyl oxidase-like protein 3
|
Research Areas for Lysyl Oxidase Homolog 3/LOXL3
Find related products by research area and learn more about each of the different research areas below.
Lipid and Metabolism
![ELISA Lysyl Oxidase Homolog 3/LOXL3 Antibody (1013328) [Unconjugated]](http://images.novusbio.com/fullsize2/Lysyl_Oxidase_Homolog_3_MAB6069_ELISA_23648.jpg)
![ELISA Lysyl Oxidase Homolog 3/LOXL3 Antibody (1013358) [Unconjugated]](http://images.novusbio.com/fullsize2/Lysyl_Oxidase_Homolog_3_MAB60691_ELISA_23649.jpg)
