Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB
Host: Mouse monoclonal
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
Lnx1 encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. [provided by RefSeq]
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
84708 |
| Alternate Names |
- EC 6.3.2.-
- ligand of numb-protein X 1ligand of numb-protein X
- LNXmulti-PDZ-domain-containing protein, E3 ubiquitin-protein ligase LNX
- MPDZ
- Numb-binding protein 1
- PDZ domain-containing ring finger protein 2
- PDZRN2E3 ubiquitin-protein ligase LNX
|
