Lefty-A Products

Description

LEFTY2 encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene.

Bioinformatics

Entrez	7044 Human
Uniprot	NM_003240 Human NP_003231 Human NP_003231 Human NP_003231.2 Human O00292 Human O00292 Human O00292.2 Human
Product By Gene ID	7044
Alternate Names	EBAFTGF-beta-4 endometrial bleeding associated factor Endometrial bleeding-associated factor LEFTAProtein lefty-A left-right determination factor 2 Left-right determination factor A LEFTYATransforming growth factor beta-4 MGC46222 Protein lefty-2 TGFB4endometrial bleeding associated factor (left-right determination, factor A;transforming growth factor beta superfamily)

Research Areas for Lefty-A

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research