KCNK10 Products

Description

KCNK10, also known as Potassium channel subfamily K member 10, has 3 isoforms, Isoform A that is 538 amino acid and app. 60 kDa, Isoform B that is 543 amino acid and app. 60 kDa, and Isoform C That is 543 amino acid and app. 60 kDa; expressed in pancreas and kidney and to a lower level in brain, testis, colon, and small intestine; belongs to the family of potassium channel proteins containing two pore-forming P domains; outwards rectifying potassium channel, produces rapidly activating and non-inactivating outward rectifier K(+) currents, activated by arachidonic acid and other naturally occurring unsaturated free fatty acids. Studies are being performed on the relationship of this protein with dentin sensitivity, brain ischemia, and ischemia. The protein has been shown to interact with AKAP150 protein and has been involved in several pathways including cholera infection, neuropathic pain-signaling in dorsal horn neurons, hepatic ABC transporters, PKA signaling, potassium transporters - outward current, gastric, and sweet taste signaling.

Bioinformatics

Entrez	54207 Human
Uniprot	NM_138317 Human NM_138318 Human NP_066984 Human NP_612190.1 Human
Product By Gene ID	54207
Alternate Names	2P domain potassium channel TREK2 K2p10.1 Outward rectifying potassium channel protein TREK-2 potassium channel subfamily K member 10 potassium channel TREK-2 potassium channel, subfamily K, member 10 TREK-2 K(+) channel subunit TREK-2 TREK2FLJ43399 TWIK-related K+ channel 2