Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse monoclonal
Species: Hu, Mu, Rt, Bv, Eq
Applications: ELISA, Flow, IHC
Host: Goat Polyclonal
Species: Hu
Applications: ICC/IF
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
HOXD10 is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as rocker-bottom foot deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.
Bioinformatics
Entrez |
Mouse Rat Human |
Uniprot |
Human Human Human |
Product By Gene ID |
3236 |
Alternate Names |
- homeo box 4D
- homeo box D10
- homeobox D10
- Homeobox protein Hox-4D
- Homeobox protein Hox-4E
- homeobox protein Hox-D10
- Hox-4.4
- HOX4DHOX4
- HOX4E
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