Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Bv
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Description
The GPAA1 gene codes for a post-translational glycosylphosphatidylinositol (GPI) anchor attachment 1 protein at the GPI transfer step but is not essential for GPI synthesis. This protein functions as a general mechanism to link proteins to the cell surface membrane and is coded before/during the formation of the carbonyl intermediate. Isoform 1 is 621 amino acids in length at 67 kDA while isoform 2 exists at 561 amino acids long at 61 kDA. GPAA1 participates in various metabolic pathways as well as post-translational protein modification through interactions with genes PRR13, ALPP, PIN1, EIF3E, and GRIK5. GPAA1 has been investigated regarding various diseases such as ataxia, hepatocellular carcinoma, and breast cancer.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
8733 |
| Alternate Names |
- anchor attachment protein 1 (Gaa1p, yeast) homolog
- GAA1 protein homolog
- GAA1glycophosphatidylinositol anchor attachment 1
- glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast)
- GPAA1P anchor attachment protein 1 homolog (yeast)
- GPAA1P anchor attachment protein 1 homolog
- GPI anchor attachment protein 1
- GPI transamidase subunit
- hGAA1glycosylphosphatidylinositol anchor attachment 1 protein
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