Species: Hu, Mu, Rt, Pm
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Bv
Applications: WB, ELISA, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
Guanylate cyclase-activating proteins (GCAPs) are calcium binding proteins that belong to the calmodulin superfamily. GCAPs without calcium are responsible for activation of photoreceptor guanylate cyclase during light adaptation. Studies have shown that the addition or subtraction of Ca2+ results in major conformational changes and the activation/deactivation of GCAP 1 and GCAP 2. It has been demonstrated that both GCAP 1 and 2 act on guanylate cyclase similarly and have approximately 50% homology between the two forms. GCAP-1 is predominantly localized in the photoreceptor outer segments, while GCAP 2 is found in retina samples.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
2979 |
| Alternate Names |
- DKFZp686E1183
- GCAP 2
- GCAP2guanylate cyclase-activating protein, photoreceptor 2
- guanylate cyclase activator 1B (retina)
- Guanylate cyclase activator 1B
- guanylyl cyclase-activating protein 2
- GUCA2
- RP48
|
Research Areas for GCAP2
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