Species: Hu
Applications: WB, Simple Western, IHC
Host: Goat Polyclonal
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IP
Host: Rabbit Monoclonal
Species: Hu
Applications: WB
Host: Mouse Monoclonal
Species: Rt
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: AC
Description
Several proteins have been identified as specific markers of prostate cancer, and they may be useful as diagnostic indicators. PSA, prostate specific antigen, is the classical indicator for transformed prostate tissue; however, in addition to being upregulated in prostate cancer, PSA is also upregulated in non-malignant conditions, such as benign prostatic hyperplasia prostate. Galectin-8, also known as prostate-specific membrane antigen (PCTA-1), is an additional prostate-specific antigen that is overexpressed only in malignant tumors and therefore is a more specific identifier of malignancies. It is a member of the galectin gene family which mediates both cell-cell and cellmatrix interactions in a manner similar to the selectin subgroup of C-type lectins.
Bioinformatics
Entrez |
Human Mouse |
Uniprot |
Human Human Human Human Human Human Human Human |
Product By Gene ID |
3964 |
Alternate Names |
- Gal-8
- galectin 8
- galectin-8
- galectin-8g
- lectin, galactoside-binding, soluble, 8
- PCTA1
- PCTA-1Po66 carbohydrate-binding protein
- Po66 carbohydrate binding protein
- Po66-CBP
- Prostate carcinoma tumor antigen 1
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