FKBP15 Products

Description

Immunophilins are a family of soluble receptors capable of binding to one of two major immunosuppressant agents; cyclosporin A (CsA) or FK506. Proteins that bind FK506 are termed FK506 Binding Proteins (FKBPs) and those that bind cyclosporin A are called cyclophilins (CyP). Immunophilins function as cis-trans peptidyl-prolyl isomerases (PPIase) whose activity is inhibited by their respective immunosuppressant compounds. Thus, immunophilins accelerate folding of some proteins both in vivo and in vitro by catalyzing slow steps in the initial folding and rearrangement of proline-containing proteins.

Bioinformatics

Entrez	23307 Human
Uniprot	NP_056073 Human Q9Y4D0 Human
Product By Gene ID	23307
Alternate Names	FK506 binding protein 15, 133kDa FK506-binding protein 133kDa FK506-binding protein 15 FKBP133 FKBP-133 FKBP-15,133 kDa FKBP PPP1R76,133 kDa FK506-binding protein regulatory subunit 76 WAFL

Research Areas for FKBP15

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Signal Transduction