Species: Rt
Applications: WB, Flow, IHC, CyTOF-ready
Host: Goat Polyclonal
Species: Rt
Applications: WB
Host: Mouse Monoclonal
Species: Rt
Applications: IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Rt
Applications: Binding Activity
Description
EphrinB proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. EphrinB molecules expressed at the membrane surface bind to the EphB family receptors on target cells during cell-to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing EphrinB on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of EphrinB is thought to be a critical component of this reverse signaling event. Recent work suggests that phosphorylation of a specific EphrinB residue (Tyr298) plays a key role in EphrinB signaling. (3, 5)
Bioinformatics
| Entrez |
Human
Rat
Mouse
|
| Uniprot |
Human
Human
Chicken
Human
|
| Product By Gene ID |
2047 |
| Alternate Names |
- EC 2.7.10
- EC 2.7.10.1
- EK6
- ELK
- EPH receptor B1
- eph tyrosine kinase 2
- EphB1
- EPH-like kinase 6
- ephrin type-B receptor 1
- EPHT2FLJ37986
- hEK6
- NETHek6
- soluble EPHB1 variant 1
- Tyrosine-protein kinase receptor EPH-2
|
