ENT1 Products

Description

ENT1 is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq]

Bioinformatics

Entrez	2030 Human
Uniprot	NM_001078177 Human NP_001071642 Human NP_001071643 Human NP_004946 Human NP_004946.1 Human Q99808 Human
Product By Gene ID	2030
Alternate Names	ENT1es-type equilibrative nucleoside transporter 1 MGC1465 MGC3778 solute carrier family 29 (nucleoside transporters), member 1 Solute carrier family 29 member 1 solute carrier family 29, member 1