Species: Hu, Mu, Rt, Bv, Ca, Ch, Ma, Pm
Applications: WB, Simple Western, ICC/IF
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AP
Description
Official Gene Symbol: CRHR2 Gen Bank Accession Number: NP_001874 Gene ID: 1395 (Human) Gene Map Locus: 7p15.1 (Human) CRHR2 is a novel member of Secretin-family-GPCR proteins that functions as a functional receptor for CRF. It is expressed as 3 isoforms; alpha, beta and gamma. These isoforms primarily differ in their N-terminal sequence and tissue distribution. Apart from CRF, other ligands of CRHR2 include UcnI, UcnII and UcnIII. CRHR2 is involved in stress responses, cardiovascular function and gastric motility. Studies on CRHR2 deficient mice suggested a central anxiolytic effect of CRHR2. Northern Blot analysis detects CRHR2 expression in brain, hypothalamus, heart, GI, lung, skeletal muscle and vasculature.
Bioinformatics
| Entrez |
Mouse
Human
Rat
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
1395 |
| Alternate Names |
- corticotropin releasing hormone receptor 2
- corticotropin-releasing factor receptor 2
- Corticotropin-releasing hormone receptor 2
- CRF2
- CRF2R
- CRFR2
- CRF-R2
- CRF-R-2
- CRFR-2
- CRH2R
- CRH-R2
- CRH-R-2
|
Research Areas for CRHR2/CRF2
Find related products by research area and learn more about each of the different research areas below.
GPCRNeuroscienceNeurotransmission
