Collagen XVII Products

Description

Collagen XVII encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Bioinformatics

Entrez	1308 Human
Uniprot	NM_000494 Human
Product By Gene ID	1308
Alternate Names	180 kDa bullous pemphigoid antigen 2 BA16H23.2 BP180alpha 1 type XVII collagen BPAG2bA16H23.2 (collagen, type XVII, alpha 1 (BP180)) bullous pemphigoid antigen 2 (180kD) Bullous pemphigoid antigen 2 Collagen 17 collagen alpha-1(XVII) chain collagen XVII, alpha-1 polypeptide collagen, type XVII, alpha 1 Collagen-17 FLJ60881 KIAA0204 LAD-1