CLCNKB Products

Description

Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which comprises at least 9 mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB result in the autosomal recessive Type III Bartter Syndrome. CLCNKA and CLCNKB are closely related (94% sequence identity), tightly linked (separated by 11 kb of genomic sequence) and are both expressed in mammalian kidney.

Bioinformatics

Entrez	1188 Human 79430 Rat
Uniprot	AAH20873.1 Human
Product By Gene ID	1188
Alternate Names	chloride channel KbClC-Kb chloride channel protein ClC-Kb chloride channel, kidney, B ClC-K2 CLCKB hClC-Kb MGC24087