CEACAM1/CD66a Products

Description

CEACAM1 encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of only two has been determined. [provided by RefSeq]

Bioinformatics

Entrez	634 Human
Uniprot	AAH14473 Human AAH14473.1 Human NM_001712 Human NP_001020083.1 Human NP_001171744 Human NP_001703 Human P13688 Human
Product By Gene ID	634
Alternate Names	antigen CD66 BGP-1 BGP1BGPBiliary glycoprotein 1 BGPI biliary glycoprotein adhesion molecule carcinoembryonic antigen-related cell adhesion molecule 1 (biliaryglycoprotein) carcinoembryonic antigen-related cell adhesion molecule 1 CD66a antigen CD66a

Research Areas for CEACAM1/CD66a

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer