Species: Hu, Mu, Rt
Applications: WB, Flow, IHC, IP
Host: Rabbit Monoclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
CDC42 is a small GTPase of the Rho subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc42, and is able to complement the yeast cdc42 1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott Aldrich syndrome protein (NWASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in at least two transcript variants.
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
|
| Product By Gene ID |
998 |
| Alternate Names |
- CDC42Hs
- cell division control protein 42 homolog
- cell division cycle 42 (GTP binding protein, 25kDa)
- cell division cycle 42 (GTP-binding protein, 25kD)
- dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD))
- dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD))
- G25K GTP-binding protein
- G25K
- growth-regulating protein
- GTP-binding protein, 25kD
- small GTP binding protein CDC42
|
