Carboxylesterase 2 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined; however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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![Immunocytochemistry Carboxylesterase 2/CES2 Antibody (720711) [Unconjugated]](http://images.novusbio.com/fullsize2/Carboxylesterase_2_MAB5657_Immunocytochemistry_11456.jpg)
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